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Human developmental biology of granulocyte colony-stimulating factor
1Department of Pediatrics, University of Florida College of Medicine, Gainesville, USA. calhoda@peds.ufl.edu
Clinics in Perinatology
|September 15, 2000
Abstract:
The availability of granulocyte colony-stimulating factor (G-CSF) has influenced the management of neonates with neutropenia. Since the first use of G-CSF in a neonate with neutropenia, much has been learned about the cellular sources and physiologic roles of G-CSF. This article reviews our present understanding of G-CSF and its cognate receptor in the fetus and neonate.