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Related Experiment Video

Updated: Jul 16, 2026

Instrumentation of Near-term Fetal Sheep for Multivariate Chronic Non-anesthetized Recordings

Instrumentation of Near-term Fetal Sheep for Multivariate Chronic Non-anesthetized Recordings

Published on: October 25, 2015

Is amniotic fluid volume influenced by a 24-hour fast?

I Wolman¹, A Groutz, I Gull

¹Ultrasound Unit, Lis Maternity Hospital, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Israel.

The Journal of Reproductive Medicine

|September 15, 2000

Summary

Fasting for 24 hours significantly reduces amniotic fluid index (AFI) in pregnant individuals. However, normal amniotic fluid volume is restored after fluid intake.

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Lumican Extraction from Amniotic Membrane and Determination of its Storage Temperature

Lumican Extraction from Amniotic Membrane and Determination of its Storage Temperature

Published on: October 14, 2022

Area of Science:

Obstetrics and Gynecology
Maternal-Fetal Medicine
Reproductive Physiology

Background:

Amniotic fluid volume is crucial for fetal development and well-being.
Factors influencing amniotic fluid levels, such as maternal diet, are of clinical interest.

Purpose of the Study:

To investigate the impact of a 24-hour fast on the amniotic fluid index (AFI).
To determine if fluid intake can reverse any observed changes in AFI.

Main Methods:

Prospective study comparing AFI in 22 fasting pregnant individuals with 25 non-fasting controls.
AFI measurements were taken after a 24-hour fast and again after one week.
Examinations were conducted by two blinded observers.

Main Results:

A statistically significant lower AFI was observed in the fasting group compared to the non-fasting group immediately after the fast (P < .01).
No significant difference in AFI was found between the groups after one week (P > .01), suggesting recovery.

Conclusions:

A 24-hour fast may lead to a temporary reduction in amniotic fluid volume.
Adequate fluid intake appears to be effective in restoring normal amniotic fluid levels.