Papillary meningioma with pleural metastasis: case report and literature review
Related Experiment Videos
J M Kros1, F Cella, S L Bakker
1Department of Pathology, University Hospital Rotterdam, The Netherlands. kros@path.fgg.eur.nl
Abstract:
Papillary meningiomas are rare meningeal tumors which are associated with a grim prognosis. These tumors usually recur locally and in some cases they metastasize. The clinical, radiological and histopathological features of a case of a papillary meningioma with a pleural metastasis in a 13-year-old boy are presented. The literature on metastasizing papillary meningiomas is reviewed. Up to now, 131 cases of papillary meningioma have been reported in the literature. Only 8 cases gave rise to metastases outside the central nervous system. The preferential site of metastasis appeared to be the lung. This is the first report of a papillary meningioma giving rise to a metastasis in the pleura.
Insights
Papillary meningiomas, rare brain tumors, can metastasize. This study reports the first case of a papillary meningioma with pleural metastasis in a child, highlighting rare extra-CNS spread.
Area of Science:
- Neurology
- Oncology
- Pathology
Background:
- Papillary meningiomas are uncommon tumors of the meninges.
- These tumors often have a poor prognosis, with frequent local recurrence and occasional metastasis.
- Metastasis outside the central nervous system (CNS) is rare but documented.
Observation:
- A case of papillary meningioma with pleural metastasis in a 13-year-old boy is presented.
- Clinical, radiological, and histopathological features of this rare presentation are detailed.
- This represents the first reported instance of papillary meningioma metastasizing to the pleura.
Findings:
- A review of 131 reported papillary meningioma cases found only 8 with extra-CNS metastases.
- The lung is the most common site for such metastases.
- Pleural metastasis from a papillary meningioma is exceptionally rare, with this being the first documented case.
Implications:
- This case expands the known metastatic potential of papillary meningiomas.
- It underscores the importance of considering rare metastatic sites in the differential diagnosis.
- Further research may elucidate mechanisms of extra-CNS spread in these tumors.
