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Molecular topology: a useful tool for the search of new antibacterials
C de Gregorio Alapont1, R García-Domenech, J Gálvez
1Departamento de Química Física, Facultad de Farmacia, Universitat de Valencia, Spain.
Bioorganic & Medicinal Chemistry Letters
|September 15, 2000
Abstract:
Molecular topology has been applied to find new lead antibacterial compounds. Among the selected compounds, hesperidin, neohesperidin and Mordant Brown 24 stand out, with minimum inhibitory concentrations 90, MIC90 < 0.3 mg/mL.