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Seropositivity to multiple sexually transmitted infections is not common
M Kibur1, P Koskela, J Dillner
1Department of Epidemiology and Biostatistics, Institute of Experimental and Clinical Medicine, Tallinn, Estonia. mari.kibur@ktl.fi
Sexually Transmitted Diseases
|September 15, 2000
Summary
Multiple sexually transmitted infections (STIs) seropositivity in women was assessed. Observed co-infections exceeded random chance, suggesting caution when using STI seropositivity as a sole indicator of sexual behavior.
Area of Science:
- Epidemiology
- Infectious Diseases
- Public Health
Background:
- Seropositivity for sexually transmitted infections (STIs) is frequently used as a proxy for sexual behavior.
- Assessing co-occurrence of STIs in women is crucial for understanding transmission dynamics.
Purpose of the Study:
- To quantify the excess of concurrent seropositivity for four STIs beyond random expectation in fertile-aged women.
- To evaluate the reliability of STI seropositivity as a sole indicator of sexual behavior.
Main Methods:
- A random sample of 1110 pregnant women in Tallinn, Estonia, was analyzed.
- Serological testing was performed for herpes simplex virus type 2, human papillomavirus type 16, HIV, Chlamydia trachomatis, and Treponema pallidum.
Main Results:
- 310 combinations of concomitant STI seropositivity were observed, significantly higher than the 193 expected by chance.
- Excess combinations were noted for individuals with two (78 extra), three (35 extra), and four (3.8 extra) STIs.
Conclusions:
- Seropositivity for multiple STIs is less common than predicted by random co-infection.
- Discrepancies suggest varying transmission probabilities and STI spread patterns.
- Relying solely on STI seropositivity to infer sexual behavior in women requires careful consideration.