Related Experiment Video
Updated: Aug 13, 2026

Invasive Hemodynamic Characterization of the Portal-hypertensive Syndrome in Cirrhotic Rats
Published on: August 1, 2018
Hepatic cirrhosis and portal hypertension in neuroblastoma
1Department of Haematology, Yorkhill NHS Trust, Glasgow, UK.
Abstract:
Hepatic portal hypertension is an unusual complication of cancer therapy. The authors report 2 children under the age of 18 months with disseminated neuroblastoma who developed cavernous transformation of the portal vein during chemotherapy. While the older child remains well, the second patient succumbed from overwhelming variceal hemorrhage as a result of this condition. Full recovery of hepatic function is not invariable following the regression of extensive liver infiltration by neuroblastoma and consideration should be given to follow-up Doppler ultrasound imaging of the hepatic portal system in affected infants.
Related Concept Videos
Cirrhosis I: Introduction
Cirrhosis II: Pathophysiology
Portal Hypertension
Hepatic Encephalopathy

