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Crystal-associated arthritis in the elderly.

C A Agudelo1, C M Wise

  • 1Section of Rheumatology, Emory University School of Medicine, Decatur, Georgia, USA.

Rheumatic Diseases Clinics of North America
|September 16, 2000
PubMed
Summary

Gout and pseudogout, caused by calcium crystals, increasingly affect older adults with atypical symptoms. Diagnosing and individualizing treatment for these crystal-induced arthropathies present ongoing clinical challenges.

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Area of Science:

  • Rheumatology
  • Crystal-induced arthritis

Background:

  • Understanding of crystal-induced arthritis, including gout and pseudogout, has advanced.
  • Gout, traditionally seen in middle-aged males, now shows increased prevalence in older populations with varied presentations.
  • Calcium pyrophosphate dihydrate crystal deposition disease is frequently observed in elderly individuals.

Purpose of the Study:

  • To highlight the evolving clinical understanding of gout and pseudogout.
  • To emphasize the diagnostic and therapeutic challenges posed by crystal-induced arthropathies in elderly patients.

Main Methods:

  • Review of clinical syndromes associated with basic calcium crystals in arthritis.
  • Analysis of prevalence and clinical features of gout and pseudogout in different demographics.

Main Results:

  • Crystal-induced arthropathies like gout and pseudogout are increasingly prevalent in older adults.
  • These conditions often present with atypical features in the elderly population.
  • Calcium pyrophosphate dihydrate crystal deposition disease is common among elderly patients.

Conclusions:

  • Accurate diagnosis of gout and pseudogout remains a clinical challenge, particularly in older patients.
  • Individualized therapy is crucial for patients with crystal-induced arthritis and co-existing medical conditions.

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