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A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma
Published on: June 4, 2017
[Drug allergies: a public health problem]
J Bousquet1, P Demoly, D Hillaire-Buys
1Clinique des Maladies Respiratoires, INSERM U454, IFR3, Hôpital Arnaud de Villeneuve, CHU de Montpellier.
Bulletin De L'Academie Nationale De Medecine
|September 16, 2000
Summary
Adverse drug reactions, including allergic and pseudoallergic types, affect many hospitalized patients. Diagnosis is challenging due to a lack of specific tools, impacting patient care and healthcare costs.
Area of Science:
- Pharmacovigilance
- Immunology
- Clinical Medicine
Context:
- Adverse drug reactions (ADRs) are a significant concern in healthcare settings.
- Allergic and pseudoallergic reactions constitute a substantial portion of ADRs.
- Current diagnostic methods for these reactions are insufficient.
Purpose:
- To review epidemiological data on allergic and pseudoallergic drug reactions.
- To highlight the incidence, mortality, and economic impact of these reactions.
- To underscore the need for improved diagnostic tools.
Summary:
- Adverse drug reactions affect 10-20% of hospitalized individuals, with up to one-third being allergic or pseudoallergic.
- Allergic reactions involve immunologic mechanisms, while pseudoallergic reactions mimic these without specific immune markers.
- Accurate diagnosis of these reactions is often difficult due to limited tools.
Impact:
- Understanding the epidemiology of these reactions is crucial for patient safety.
- This review provides insights into the incidence, mortality, and cost associated with drug hypersensitivity.
- Highlights the gap in diagnostic capabilities for allergic and pseudoallergic drug reactions.
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