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Can vitreous fluorophotometry predict the necessity for photocoagulation? A 5-year follow-up study
1Department of Ophthalmology, Aalborg Sygehus Syd, Denmark.
Purpose:
To examine the long-term outcome of vitreous fluorophotometry including the predictability of retinopathic proliferative development in diabetic subjects.
Methods:
21 diabetic subjects were examined by long-term kinetic vitreous fluorophotometry and their barrier properties, as revealed by a permeability-index, were compared to a group of normal subjects. 13 diabetics were classified as having a high permeability-index, while 8 diabetics were classified as having a low permeability-index. The two groups were followed for 5 years with regard to development of proliferative retinopathy.
Results:
6 of 13 diabetics with a high permeability-index developed proliferative retinopathy within the 5-year follow-up period. This was in contrast to the low permeability-index group where none of 8 diabetics developed proliferative retinopathy.
Conclusion:
An increased permeability-index points towards an increased risk of development of proliferative retinopathy.