Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Exercise for knee osteoarthritis.

K Baker1, T McAlindon

  • 1The Boston University Multipurpose Arthritis and Musculoskeletal Disease Center, Boston University School of Medicine, Massachusetts 02118, USA. krbaker@bu.edu

Current Opinion in Rheumatology
|September 16, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A 107 Gene Nanostring Assay Effectively Translates the Cancer Genome Atlas, and Tumour Microenvironment Gastric Cancer Molecular Classification to a Patient-Derived Organoid Model.

Genes, chromosomes & cancer·2025
Same author

Computational design of highly signalling-active membrane receptors through solvent-mediated allosteric networks.

Nature chemistry·2025
Same author

The sustainability of exercise following colorectal surgery: A qualitative study of participants in the PREPARE-ABC trial.

Clinical rehabilitation·2024
Same author

Investigation of the gut microbiome, bile acid composition and host immunoinflammatory response in a model of azoxymethane-induced colon cancer at discrete timepoints.

British journal of cancer·2022
Same author

Excessive alcohol consumption and the risk of knee osteoarthritis: a prospective study from the Osteoarthritis Initiative.

Osteoarthritis and cartilage·2022
Same author

Understanding and addressing vaccine hesitancy in the context of COVID-19: development of a digital intervention.

Public health·2021
Same journal

New approaches to the management of cutaneous lupus.

Current opinion in rheumatology·2026
Same journal

"Updates in chronic nonbacterial osteomyelitis: emerging insights across the age spectrum".

Current opinion in rheumatology·2026
Same journal

Difficult-to-treat, complex-to-manage, treatment-refractory spondyloarthritis: semantics or substance?

Current opinion in rheumatology·2026
Same journal

Update on IgA nephropathy: implications for treatment in IgA vasculitis: a guide for rheumatologists.

Current opinion in rheumatology·2026
Same journal

Polyarticular juvenile idiopathic arthritis: insights from genetic studies on disease risk and pathogenesis.

Current opinion in rheumatology·2026
Same journal

Immune dysregulation in children with Down syndrome: clinical implications and emerging therapies.

Current opinion in rheumatology·2026
See all related articles

Exercise interventions show promise for improving knee osteoarthritis pain and disability, though results vary. Further research is needed to optimize exercise protocols for public health impact.

Area of Science:

  • Orthopedics
  • Rehabilitation Medicine
  • Sports Medicine

Background:

  • Knee osteoarthritis (KOA) significantly impacts quality of life through pain, loss of function, and disability.
  • Current treatments primarily target pain relief, often overlooking distinct factors contributing to disability.
  • Existing therapeutic approaches demonstrate greater efficacy in pain reduction than in functional improvement.

Purpose of the Study:

  • To evaluate the effectiveness of exercise interventions in managing knee osteoarthritis outcomes.
  • To explore the relationship between exercise, pain reduction, and functional improvement in KOA patients.
  • To identify factors contributing to variability in exercise treatment outcomes for KOA.

Main Methods:

  • Systematic review and meta-analysis of studies investigating aerobic and strength training for knee osteoarthritis.

Related Experiment Videos

  • Analysis of diverse study designs, exercise protocols, and participant characteristics.
  • Assessment of reported outcomes focusing on pain levels and functional disability.
  • Main Results:

    • A majority of reviewed studies reported positive effects of exercise on pain and/or disability in knee osteoarthritis.
    • Considerable variability exists in reported outcomes, potentially due to differences in study methodologies and participant populations.
    • Exercise interventions appear more effective in addressing disability than pain alone.

    Conclusions:

    • Exercise, encompassing aerobic and strength training, presents a viable strategy for managing knee osteoarthritis.
    • The precise mechanisms through which exercise influences KOA symptoms require further elucidation.
    • Development of standardized exercise protocols could enhance public health interventions for knee osteoarthritis management.