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Updated: Aug 14, 2026

Real-time Monitoring of Ligand-receptor Interactions with Fluorescence Resonance Energy Transfer
Published on: August 20, 2012
Resonance-mediated chemical reaction: F+HD-->HF+D
Skodje1, Skouteris, Manolopoulos
1Institute of Atomic and Molecular Sciences, Academia Sinica, Taipei, Taiwan 106, Republic of China and Department of Chemistry, University of Colorado, Boulder, Colorado 80309.
Abstract:
Conclusive evidence is presented for the existence of a reactive resonance in the F+HD reaction. In a molecular beam experiment, the resonance appears in the integral cross section as a distinct steplike feature, while in the differential cross section it is manifested as sharply varying forward-backward peaks in the product distribution. A detailed analysis of the quantum dynamics establishes that a reactive resonance localized in the transition-state region is responsible for these remarkable observations. At collision energies below 1 kcal/mol, the reaction proceeds almost exclusively through resonant tunneling with very little contribution from the more conventional direct mechanism.
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