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Updated: Aug 3, 2026

Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
CT evaluation of renovascular disease
A Kawashima1, C M Sandler, R D Ernst
1Department of Radiology, University of Texas Medical School, Houston 77026, USA. akira.kawashima@uth.tmc.edu
Insights
Computed tomography (CT) is vital for diagnosing renovascular diseases. Enhanced CT scans effectively reveal renal infarcts, ischemia, and trauma-related artery blockages, improving patient management.
Area of Science:
- Radiology
- Vascular Imaging
- Nephrology
Background:
- Computed tomography (CT) is a crucial imaging modality for assessing renovascular diseases.
- Both nonenhanced and contrast-enhanced CT techniques offer distinct diagnostic capabilities for renal pathology.
- CT plays a role in identifying renal manifestations of systemic diseases and trauma.
Purpose of the Study:
- To highlight the utility of computed tomography (CT) in the evaluation and management of primary renovascular disease.
- To detail the specific applications of nonenhanced and contrast-enhanced CT in diagnosing various renal vascular conditions.
- To emphasize the role of advanced CT techniques in visualizing renal arteries and detecting vascular lesions.
Main Methods:
- Utilizing nonenhanced CT to identify renal hemorrhage, calcifications, and masses.
- Employing contrast-enhanced CT to detect nephrographic abnormalities, infarcts, ischemia, and arteriovenous communications.
- Leveraging helical CT with multiplanar and 3D reconstructions for direct imaging of proximal renal arteries.
Main Results:
- Nonenhanced CT effectively demonstrates hemorrhage, calcifications, and masses.
- Contrast-enhanced CT is essential for identifying vascular processes like infarcts, stenosis-related ischemia, and arteriovenous communications.
- CT can diagnose main renal artery occlusion in trauma and identify signs of acute or chronic renal vein thrombosis.
Conclusions:
- Computed tomography is indispensable for diagnosing and managing renovascular diseases.
- Contrast-enhanced CT provides critical information on renal perfusion and vascular integrity.
- Advanced CT techniques significantly enhance the visualization and detection of renal artery pathologies.
Abstract:
Computed tomography (CT) plays an important role in evaluation and management of primary renovascular disease. Nonenhanced CT is useful for demonstrating renal hemorrhage, renal parenchymal or vascular calcifications, and masses. Contrast material-enhanced CT is essential to identify global or regional nephrographic abnormalities resulting from the vascular process (eg, renal infarcts, ischemia secondary to renal artery stenosis, arteriovenous communications). In addition, renal manifestations of a systemic disease (eg, vasculitis, thromboembolic disease) can be seen at CT. In trauma, occlusion of the main renal artery can be accurately diagnosed with contrast-enhanced CT. In cases of spontaneous renal hemorrhage without an apparent cause (eg, vasculitis, coagulopathy), a careful CT study should be performed to exclude renal cell carcinoma. The presence of fat in a hemorrhagic renal mass larger than 4 cm in diameter is characteristic of angiomyolipoma complicated by hemorrhage. Acute renal vein thrombosis appears as a clot in a distended renal vein, whereas renal vein retraction with collateral vessels is highly indicative of chronic thrombosis. Helical CT, especially with multiplanar two-dimensional and three-dimensional reconstruction following an intravenous injection of iodinated contrast material, has greatly improved our ability to directly image the proximal renal arteries and detect vascular lesions.
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