Related Experiment Video
Updated: Aug 21, 2026

09:03
Murine Corneal Transplantation: A Model to Study the Most Common Form of Solid Organ Transplantation
Published on: November 17, 2014
Immunization with alpha-toxin toxoid protects the cornea against tissue damage during experimental Staphylococcus
E B Hume1, J J Dajcs, J M Moreau
1Department of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, Louisiana 70112, USA.
Infection and Immunity
|September 19, 2000
Abstract:
Alpha-toxin is a major virulence factor in Staphylococcus aureus keratitis. Active or passive immunization with alpha-toxin toxoid could protect against corneal damage. Results show that either form of immunization did not kill bacteria but did significantly protect against corneal pathology, especially epithelial erosion.

