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Related Experiment Video

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Mouse in Utero Electroporation: Controlled Spatiotemporal Gene Transfection
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Subicular input from temporal cortex in the rhesus monkey.

G W Van Hoesen, D L Rosene, M M Mesulam

    Science (New York, N.Y.)
    |August 10, 1979
    PubMed
    Summary

    The subicular cortices link the temporal lobe cortex and hippocampus in primates. These areas are crucial for interaction between the hippocampal formation and association cortices.

    Area of Science:

    • Neuroscience
    • Primate Brain Anatomy

    Background:

    • The subicular cortices are key components of the primate hippocampal formation.
    • They serve as a crucial anatomical bridge between the cerebral cortex and the hippocampus.

    Purpose of the Study:

    • To elucidate the connectional role of subicular cortices.
    • To understand their significance in information processing between the hippocampus and temporal lobe association cortices.

    Main Methods:

    • Anatomical tracing studies in primate brains.
    • Analysis of cortical and hippocampal connectivity patterns.

    Main Results:

    • Subicular cortices demonstrate direct connections with most temporal lobe cortices, excluding primary sensory areas.

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  • These connections highlight the subiculum's role as an integration hub.

    • Conclusions:

    • The subicular cortices play a pivotal role in mediating interactions between the hippocampal formation and association cortices.
    • Their extensive connectivity underscores their importance in higher cognitive functions involving memory and association.