Technique for vestibular neurotomy in the rat

Area of Science:

• Otolaryngology
• Neurosurgery
• Animal Models

Background:

• Vestibular neurotomy is a surgical procedure to sever the vestibular nerve.
• Accurate and minimally invasive techniques are crucial for research involving the vestibular system.

Purpose of the Study:

• To develop and describe a novel surgical technique for performing vestibular neurotomy in a rat model.
• To enable precise targeting of the vestibular nerve without direct visualization.

Main Methods:

• A transmeatal approach was utilized, involving removal of the tympanic membrane and ossicles.
• Access to the auditory bulla was achieved through the external auditory meatus.
• The pterygopalatine artery was cauterized, and an electrode was introduced via the oval window for nerve cauterization.

Main Results:

• The described technique successfully permits access to the auditory bulla.
• The vestibular branch of the VIII cranial nerve can be effectively cauterized using an electrode introduced through the oval window.
• The procedure can be performed without the need for direct visualization of the nerve.

Conclusions:

• A reproducible surgical technique for vestibular neurotomy in rats has been established.
• This method offers a viable approach for research requiring targeted vestibular nerve ablation in animal models.
• The technique's ability to proceed without direct visualization may enhance its applicability and reduce potential complications.