Related Experiment Videos
Phytochemical flavones isolated from Scutellaria barbata and antibacterial activity against methicillin-resistant
Y Sato1, S Suzaki, T Nishikawa
1Laboratory of Microbial Chemistry, Faculty of Pharmaceutical Sciences, University of Tokushima, Sho-machi 1-78, 770-8505, Tokushima, Japan.
Journal of Ethnopharmacology
|September 21, 2000
Abstract:
A crude extract prepared from Scutellaria barbata D. Don (Lamiaceae) was analyzed in the effort to discover antibacterial compounds against high-level strains of methicillin-resistant Staphylococcus aureus (MRSA). Apigenin and luteolin were isolated from the plant as active constituents against the bacteria. These flavonoid congeners were selectively toxic to S. aureus, including the MRSA and methicillin-sensitive S. aureus strains.