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Ex Vivo Infection of Murine Epidermis with Herpes Simplex Virus Type 1
Published on: August 24, 2015
[Outbreak of infectious erythema at a urban health center]
A I Revilla Grande1, T Carro García, M Sánchez de Dios
1Unidad Docente de Soria, Centro de Salud Soria Norte, Soria. javierherranz@arrakis.es
Insights
An infectious erythema outbreak occurred in Soria Norte, confirmed by serology in 84% of pediatric patients. The disease was generally benign, with characteristic facial rash being the most common symptom.
Area of Science:
- Pediatric Infectious Diseases
- Clinical Virology
- Epidemiology
Context:
- An outbreak of infectious erythema (also known as fifth disease) was suspected in pediatric clinics.
- The study was conducted at the Soria Norte Health Centre between April and August 1998.
- This research focuses on a specific regional outbreak to understand its characteristics.
Purpose:
- To analyze the clinical and serological features of an infectious erythema outbreak.
- To confirm the presence of the outbreak through diagnostic analysis.
- To provide data for therapeutic and preventive strategies.
Summary:
- A cross-sectional study analyzed 25 children presenting with symptoms suggestive of infectious erythema.
- Clinical manifestations included a prominent facial rash (100%), followed by trunk/limb rash (57%).
- Serological confirmation was achieved in 84% of cases, with no reported complications and a benign overall disease course.
Impact:
- Confirms a localized outbreak of infectious erythema, aiding public health awareness.
- Highlights the utility of serological confirmation for outbreak management.
- Emphasizes the typically mild nature of infectious erythema, informing clinical expectations and reducing unnecessary alarm.
Objectives:
To analyse the clinical and serological characteristics of an outbreak of infectious erythema in patients attending the two paediatrics clinics at the Soria Norte Health Centre.
Design:
Cross-sectional, descriptive study.
Setting:
Paediatrics clinics of the Soria Norte Health Centre.
Patients:
Once the outbreak was suspected, the study was conducted on children with a clinical picture suggesting infectious erythema who attended successively two Soria Norte paediatrics clinics between April and August 1998 and who consented to the analyses.
Interventions:
The clinical symptoms, serology, haemogram and evolution of 25 patients were recorded.
Results:
25 patients of the total were studied and diagnostic suspicion was confirmed in 84% of the cases. There were no differences between sexes, with an average age of 6.1, SD 2.015. The most constant clinical sign was exanthem on the cheeks, present in 100% of the cases confirmed, followed by 57% exanthem on the trunk and limbs, 9.5% adenopathies and 4.7% temperature. No complications were found in any case.
Conclusions:
The results of this study confirm the existence of an outbreak of infectious erythema in our area. Serological confirmation of an outbreak is useful and can lay the basis for a proper therapeutic and preventive focus (against possible complications). We highlight the generally benign nature of the disease.
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