Alternative medicines elevate blood leads in Omani children referred for extensive investigation

P M Timms1, A M Bold

  • 1Department of Clinical Biochemistry, St Bartholomew's Hospital, London, UK.

Insights

Elevated blood lead levels are common in Omani children under 12, with 22-45% exceeding desirable limits. Higher levels were observed in Muscat, particularly in children with cancer or thalassemia.

Area of Science:

  • Environmental Health
  • Pediatrics
  • Toxicology

Background:

  • Lead exposure poses significant health risks to children.
  • Routine screening is crucial for identifying elevated blood lead levels (BLLs).
  • Understanding geographical variations in BLLs is important for public health interventions.

Purpose of the Study:

  • To determine the frequency of elevated BLLs in Omani children undergoing routine investigations.
  • To identify potential geographical differences in BLLs across Oman.
  • To investigate if specific clinical settings are associated with higher BLLs.

Main Methods:

  • Analysis of 529 blood samples from children under 12 years old.
  • Samples were randomly selected from four locations: Royal Hospital (Muscat), Nizwa, Sur, and Sohar.
  • Blood lead levels were measured and compared against Centers for Disease Control and Prevention (CDC) criteria.

Main Results:

  • Between 22% and 45% of children in all surveyed areas had BLLs higher than desirable.
  • The highest prevalence of elevated BLLs was observed at the Royal Hospital in Muscat.
  • Children in pediatric oncology or thalassaemia clinics showed the highest BLLs.

Conclusions:

  • Elevated BLLs are a significant concern among Omani children, even without clinical suspicion of poisoning.
  • Geographical variations exist, with higher levels noted in the capital.
  • Children with specific chronic conditions may be at increased risk, warranting further investigation.

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