[Helicobacter pylori infection in children without dyspepsia in Curundu and Parque Lefevre]

Area of Science:

• Pediatric Infectious Diseases
• Microbiology
• Public Health

Background:

• Helicobacter pylori infection is a significant global health concern.
• Understanding seroprevalence in pediatric populations is crucial for public health strategies.
• Previous studies highlight varying prevalence rates across different regions and age groups.

Purpose of the Study:

• To determine the seroprevalence of Helicobacter pylori infection in healthy children.
• To investigate the correlation between age and H. pylori seropositivity.
• To assess the impact of household sanitation on H. pylori seroprevalence.

Main Methods:

• Enzyme-Linked Immunosorbent Assay (ELISA) IgG was used to detect H. pylori antibodies.
• The study included 83 consecutive healthy children.
• Participants were categorized into age groups (0-5, 6-10, 11-15 years) and by sanitation status.

Main Results:

• Overall seroprevalence of H. pylori was 55% among the studied children.
• Seropositivity rates varied by age: 55% (0-5 years), 47% (6-10 years), and 67% (11-15 years).
• Children without in-home sanitation showed significantly higher seropositivity (86%) compared to those with sanitation (47%).

Conclusions:

• Helicobacter pylori infection is common in healthy children, with higher rates in older children.
• Inadequate household sanitation is a critical risk factor for H. pylori infection in pediatric populations.
• Public health interventions should focus on improving sanitation to reduce H. pylori transmission in children.