Related Experiment Video
Updated: Jul 13, 2026

Determining heat and mechanical pain threshold in inflamed skin of human subjects
Published on: January 14, 2009
Cerebral Responses to Warmth and Heat and Cold Pain Measured by Positron Emission Tomography
1Department of Internal Medicine (Nuclear Medicine), The University of Michigan, B1G412 University Hospital, Ann Arbor, MI 48109-0028, USA.
Abstract:
Phasic heat and tonic cold stimuli that have different temporal patterns, afferent fiber activations, and perceived pain characteristics produce a shared pattern of cerebral activation in addition to modality specific activations. These patterns are different from the cerebral representation of innocuous temperature sensation. Functional brain imaging techniques provide an opportunity to study somatosensory organization in conscious humans under physiologic conditions, despite certain limitations of imaging modalities.
Related Concept Videos
Thermosensation
Responses to Heat and Cold Stress
Decreased Body Temperature
Assessing Body Temperature - Temporal Artery
Step 1: Perform hand hygiene and don a fresh pair of gloves to prevent cross-infection and ensure patient safety.
Step 2: Explain the procedure to the patient to establish trust. Clear communication establishes trust with the patient, ensures they understand what to expect, promotes cooperation, and enhances comfort during the procedure.
Step 3: Assess the patient's forehead...
Pain

