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Related Concept Videos

Depression: Overview01:18

Depression: Overview

Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
Psychodynamic Therapy01:29

Psychodynamic Therapy

Psychodynamic therapies emphasize the exploration of unconscious processes and early childhood experiences as fundamental contributors to psychological difficulties. These therapies, deeply rooted in Freud's psychoanalytic theory, aim to uncover and resolve unconscious conflicts, granting individuals insights that promote emotional and behavioral healing. Contemporary psychodynamic approaches have evolved, integrating a broader range of influences and methodologies while still valuing the...
Cognitive Therapy01:25

Cognitive Therapy

Cognitive therapy, pioneered by Aaron T. Beck in the 1960s, is a structured approach to addressing psychological distress by focusing on the influence of thoughts on emotions and behaviors. All cognitive therapies involve the basic assumption that human beings have control over their feelings, and that how individuals feel about something depends on how they think about it. Unlike psychoanalytic methods that delve into unconscious processes or humanistic approaches emphasizing...
Increased Intracranial Pressure l: Introduction01:14

Increased Intracranial Pressure l: Introduction

Intracranial hypertension is a sustained elevation of intracranial pressure (ICP) above 22 mm Hg. In supine adults, normal ICP is ~7–15 mm Hg.The rigid, nonexpandable cranium contains three components—brain tissue, blood, and cerebrospinal fluid (CSF)—that total ~1,700 mL in a typical adult: 1,400 mL brain (~80%), 150 mL blood (~10%), and 150 mL CSF (~10%). According to the Monro–Kellie doctrine, total intracranial volume is effectively fixed. When one component expands, CSF and venous blood...
Increased Intracranial Pressure ll: Pathophysiology01:29

Increased Intracranial Pressure ll: Pathophysiology

Increased intracranial pressure (ICP) refers to a potentially life-threatening rise in pressure inside the skull. This usually happens when there is a major change in the volume of brain tissue, blood, or cerebrospinal fluid (CSF) — the three components inside the skull. According to the Monro-Kellie doctrine, if the volume of one component increases, the volumes of the other components must decrease to maintain normal pressure. If this does not happen, ICP rises.The process often begins with...

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Related Experiment Video

Updated: Jul 27, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
10:39

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

Chronic Daily Headache: Theory to Therapy.

Wheeler1

  • 1Pain and Orthopedic Neurology, P.A., Charlotte Spine Center, 2001 Randolph Road, Charlotte, NC 28207, USA.

Current Review of Pain
|September 22, 2000
PubMed
Summary

Chronic daily headaches often stem from brain stem processing issues, not serious illness. Management focuses on behavioral changes and avoiding medication overuse for better outcomes.

Area of Science:

  • Neurology
  • Pain Medicine
  • Neuroscience

Background:

  • Headaches are a common reason for seeking medical care in the US.
  • While sometimes indicating serious illness, headaches frequently arise from primary disorders in brain stem nociceptive processing.
  • Chronic daily headache can evolve from episodic types, often linked to medication overuse and disability.

Purpose of the Study:

  • To review the pathophysiology and evolutionary mechanisms of chronic headache.
  • To discuss revised classifications and nosology for headache disorders.
  • To outline effective management strategies for chronic craniofacial pain.

Main Methods:

  • Review of recent scientific and clinical observations.
  • Integration of pathoanatomic models for persistent headache.

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Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache

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Related Experiment Videos

Last Updated: Jul 27, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
10:39

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

Investigating Migraine-Like Behavior Using Light Aversion in Mice
05:23

Investigating Migraine-Like Behavior Using Light Aversion in Mice

Published on: August 11, 2021

Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache
05:40

Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache

Published on: July 29, 2021

  • Analysis of International Headache Society (IHS) classifications.

    • Main Results:

    • Chronic headaches are often primary disorders of brain stem modulation.
    • Understanding pathophysiology has led to proposed changes in headache classification.
    • Persistent headaches can be explained by integrated pathoanatomic models.

    Conclusions:

    • Chronic daily headache is a complex syndrome often associated with medication overuse.
    • Revised classifications reflect a better understanding of headache pathophysiology.
    • Management should prioritize behavioral changes and avoiding medication overuse.