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Interleukin 18 (IL-18) levels in patients with sepsis
1Critical Care and Emergency Center, Iwate Medical University, Morioka, Japan.
Journal of Medicine
|September 22, 2000
Abstract:
IL-18 levels in the blood of 13 sepsis patients were assessed. The IL-18 values were significantly correlated with their Acute Physiology and Chronic Health Evaluation (APACHE) II scores, and they were a good reflection of the severity of the disease. There was also a strong correlation between the IL-18 values and the patients' inflammatory cytokine levels. The results suggested strong involvement of IL-18 in the pathogenesis of sepsis.