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Hyperbaric oxygen therapy in parenchymal liver disease
M Bhattacharya1, P G Kumar, T K Sahni
1Dept of Medicine and Underwater Medicine, Naval Hospital, Asvini, Colaba, Bombay.
The Journal of the Association of Physicians of India
|February 1, 1996
Summary
Hyperbaric oxygen therapy (HOT) shows promise for liver disease patients, accelerating recovery and improving well-being. This treatment led to faster normalization of liver function and reduced hospital stays in a controlled study.
Area of Science:
- Hepatology
- Hyperbaric Medicine
Background:
- The efficacy of hyperbaric oxygen therapy (HOT) for liver disease remains largely unestablished.
- Liver disease management often involves supportive care, with limited options for accelerating recovery.
Purpose of the Study:
- To investigate the use and efficacy of hyperbaric oxygen therapy (HOT) in patients with liver disease.
- To compare outcomes between patients receiving HOT and those receiving conventional therapy.
Main Methods:
- A prospective control study involving 60 male patients with liver disease and serum bilirubin over 10 mg/dl.
- Patients were divided into two groups: 30 receiving HOT and 30 receiving conventional therapy.
- Both groups included a similar proportion of Hepatitis B virus surface antigen (HbsAg) positive cases.
Main Results:
- Patients undergoing HOT demonstrated faster recovery, improved appetite, and an earlier sense of well-being.
- Quicker resolution of pruritus, normalization of liver function, and HbsAg negativity were observed in the HOT group.
- The duration of hospital stay and convalescence was significantly shorter for patients treated with HOT.
Conclusions:
- Hyperbaric oxygen therapy (HOT) appears to be a safe and effective adjunct treatment for selected liver disease patients.
- HOT may accelerate recovery, improve clinical symptoms, and shorten hospitalization periods in liver disease management.
- Further research is warranted to fully establish the role of HOT in diverse liver disease populations.