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Kirkinine, a new daphnane orthoester with potent neurotrophic activity from Synaptolepis kirkii
1Department of Organic Chemistry, Faculty of Agricultural and Applied Biological Sciences, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Journal of Natural Products
|September 23, 2000
Abstract:
The bioassay-guided fractionation of a dichloromethane extract from the roots of Synaptolepis kirkii using neuronal viability as a model allowed the isolation of the new daphnane orthoester kirkinine (1a) as a powerful neurotrophic constituent.