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Bioactive carotanes from Trichoderma virens
F A Macías1, R M Varela, A M Simonet
1Departamento de Química Orgánica, Facultad de Ciencias, Universidad de Cádiz, Apdo. 40, 11510-Puerto Real, Cádiz, Spain. famacias@uca.es
Journal of Natural Products
|September 23, 2000
Abstract:
Four new metabolites with carotane skeletons, trichocaranes A (1), B (2), C (3), and D (4), were isolated from Trichoderma virens and their structures established by the interpretation of NMR and mass spectroscopic data. The trichocaranes significantly inhibited the growth of etiolated wheat coleoptiles: 40% at 10(-4) M with 1 and 2 and 86% at 10(-3) M with 3.