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Fetal biometric parameters, twin type and birth weight difference. A longitudinal study.

C Charlemaine1, M Duyme, Y Ville

  • 1Unité de Recherches d'Epidémiologie Génétique, INSERM U 155, Laboratoire d'Anthropologie Biologique, Université Paris VII, Tour 16, 3eétage, Case 7041, 2 Place Jussieu, 75005 05, Paris, France.

European Journal of Obstetrics, Gynecology, and Reproductive Biology
|September 23, 2000
PubMed
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Twin type and birth weight discordancy significantly impact fetal growth measurements. Abdominal area may indicate obstetric complications in twins, highlighting the importance of detailed twin analysis.

Area of Science:

  • Perinatology
  • Fetal Medicine
  • Maternal-Fetal Medicine

Background:

  • Twin pregnancies present unique growth dynamics compared to singleton gestations.
  • Understanding factors influencing fetal growth in twins is crucial for optimizing perinatal outcomes.
  • Birth weight discordancy is a known risk factor for adverse outcomes in twin pregnancies.

Purpose of the Study:

  • To investigate the impact of twin type (zygosity, chorionicity) and birth weight difference on fetal biometric measurements.
  • To analyze these relationships across different gestational ages (18, 23, 28, and 32 weeks).
  • To identify specific biometric parameters associated with discordant growth in twins.

Main Methods:

  • A prospective, longitudinal study of 75 twin pairs (150 fetuses) without twin-twin transfusion syndrome.

Related Experiment Videos

  • Classification of twin pairs into dizygotic, monochorionic, and dichorionic-monozygotic groups.
  • Division of twin pairs into two groups based on birth weight difference: <15% (Group I) and >=15% (Group II).
  • Evaluation of various ultrasound-derived fetal biometric parameters and intrapair differences.
  • Main Results:

    • Significant associations between twin type, gestational age, and fetal biometric parameters were observed in dizygotic and monochorionic twins.
    • Intrapair differences in most fetal parameters were significantly higher in the discordant growth group (Group II) compared to the concordant group (Group I).
    • Abdominal circumference (AC) and cerebellar parameters showed less significant intrapair differences related to birth weight discordancy.
    • Specific biometric parameters like femur length (FL) and transverse cerebellar diameter showed differential associations with birth weight discordancy depending on zygosity type.

    Conclusions:

    • Fetal biometric parameters are largely associated with birth weight discordancy in twin pregnancies.
    • Abdominal area measurements may serve as a valuable indicator for identifying twins at risk of obstetric complications.
    • This study provides novel insights by analyzing twin samples stratified by both twin type and birth weight discordancy.