Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Simple modified ultrafiltration.

G J Myers1, R B Leadon, L B Mitchell

  • 1Cardiovascular Perfusion Services and Pediatric Cardiovascular Surgery, IWK-Grace Health Center, Halifax, Nova Scotia, Canada. edit@ns.sympatico.ca

Perfusion
|September 23, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

KEAP1 polymorphisms and neurodevelopmental outcomes in children with exposure to prenatal MeHg from the Seychelles Child Development Study Nutrition Cohort 2.

Neurotoxicology·2023
Same author

A pilot study investigating the relationship between serum Se concentrations and Selenoprotein P activity at 28wks gestation in a high fish-eating sub-cohort of Seychellois pregnant women - CORRIGENDUM.

The Proceedings of the Nutrition Society·2023
Same author

Associations between maternal inflammation during pregnancy and infant birth outcomes in the Seychelles Child Development Study.

Journal of reproductive immunology·2019
Same author

Putting findings from the Seychelles Child Development Study into perspective: The importance of a historical special issue of the Seychelles Medical and Dental Journal.

Neurotoxicology·2019
Same author

Associations of blood mercury and fatty acid concentrations with blood mitochondrial DNA copy number in the Seychelles Child Development Nutrition Study.

Environment international·2019
Same author

Maternal polymorphisms in glutathione-related genes are associated with maternal mercury concentrations and early child neurodevelopment in a population with a fish-rich diet.

Environment international·2018
Same journal

Trileaflet mitral valve in hypertrophic obstructive cardiomyopathy: A rare anatomical variant requiring surgical intervention.

Perfusion·2026
Same journal

Corrigendum to: "A comparison of continuous blood gas monitors during cardiopulmonary bypass LivaNova B-capta, terumo CDI 500, spectrum medical M4".

Perfusion·2026
Same journal

ROTEM versus conventional coagulation tests in evaluating coagulopathy and transfusion requirement in ECMO patients: A retrospective study.

Perfusion·2026
Same journal

Safety and efficacy of transcatheter aortic valve replacement (TAVR) vs. surgical aortic valve replacement (SAVR) in patients with bicuspid aortic stenosis: A Systematic review and meta-analysis.

Perfusion·2026
Same journal

External validation of the population pharmacokinetic model of meropenem in patients undergoing neonatal extracorporeal membrane oxygenation and continuous renal replacement therapy.

Perfusion·2026
Same journal

Hydrogen ion (pH) and gas behavior during deep hypothermic cardiopulmonary bypass: Physiology and clinical implications.

Perfusion·2026
See all related articles

Simplified modified ultrafiltration (SMUF) offers a straightforward, effective method for post-cardiac surgery fluid removal. This technique significantly improves patient parameters with a short learning curve and reduced complications.

Area of Science:

  • Cardiovascular Surgery
  • Nephrology
  • Perfusion Technology

Background:

  • Modified ultrafiltration (MUF) is a crucial technique for fluid removal after cardiopulmonary bypass.
  • Existing MUF methods can be complex to implement and manage during surgery.

Purpose of the Study:

  • To develop and evaluate a simplified modified ultrafiltration (SMUF) technique.
  • To assess the efficacy and safety of SMUF in pediatric and neonatal cardiac surgery patients.

Main Methods:

  • A novel venoarterial MUF approach was designed, withdrawing blood from the right atrium and reinfusing into the aortic cannula.
  • Evaluated simplicity of operation, setup, and analysis of key hemodynamic and fluid parameters in 12 patients.
  • Compared SMUF performance against established MUF methods.

Related Experiment Videos

Main Results:

  • SMUF demonstrated comparable effectiveness to existing MUF techniques in improving measured parameters.
  • Significant improvements were observed in hemoglobin, hematocrit, total proteins, and colloid osmotic pressure.
  • The SMUF technique showed a very short learning curve and was well-accepted by surgical and anesthesia teams.

Conclusions:

  • Simplified modified ultrafiltration (SMUF) is a safe, effective, and easily implemented method for post-cardiac bypass fluid management.
  • SMUF offers advantages in operational simplicity, setup ease, and reduced complication risk.
  • This technique allows for continuous ultrafiltration during bypass using a single circuit design.