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[Intoxication with propylene glycol in two horses]
L van den Wollenberg1, C H Pellicaan, K Müller
1Faculteit der Diergeneeskunde, Hoofdafdeling Gezondheidszorg Paard, discipline Inwendige Ziekten, CM Utrecht. L.vandenWollenberg@vet.uu.nl
Tijdschrift Voor Diergeneeskunde
|September 26, 2000
Summary
Accidental administration of propylene glycol to horses can cause severe D-lactate intoxication, leading to central nervous system depression and metabolic acidosis. Prompt veterinary intervention ensures full recovery from these dangerous equine poisoning incidents.
Area of Science:
- Veterinary Medicine
- Equine Health
- Toxicology
Background:
- Propylene glycol and mineral oil are commonly used by veterinarians.
- Similar packaging and appearance of these substances can lead to accidental medication errors.
Observation:
- Two horses mistakenly received propylene glycol instead of mineral oil.
- Intensive medical therapy, including intravenous fluids, was initiated upon discovery of the error.
Findings:
- Large doses of propylene glycol can cause dangerous D-lactate intoxication in horses.
- Clinical signs include central nervous system depression, metabolic acidosis, colic, diarrhea, and respiratory distress.
Implications:
- Accidental propylene glycol poisoning in horses requires immediate and adequate veterinary intervention.
- Increased awareness and distinct labeling are crucial to prevent similar medication errors in equine practice.