Related Experiment Videos
[Treatment of stage I germ cell tumors of the testis]
L Santomé Couto1, J M Tabernero Caturla, H Villavicencio Mavrich
1Servicio de Oncología Médica, Hospital General Vall d'Hebron, Barcelona.
Objective:
To review the advantages, disadvantages and efficacy of the different therapeutic options for stage I seminoma and nonseminomatous germ cell testicular tumors.
Methods:
The literature on the treatment of stage I germ cell testicular tumors was reviewed.
Results/Conclusions:
Germ cell tumors of the testis constitute 1-1.5% of neoplasms in the male, accounting for 95% of testicular neoplasms, and is the most common solid tumor in men aged 20-35 years. Currently, 70% of the patients with seminoma and 50% of the patients with nonseminomatous germ cell testicular tumors are diagnosed in stage I. Radiotherapy following orchidectomy has classically been utilized in the treatment of stage I germ cell testicular tumors. Postoperative radiation therapy is currently being replaced by close patient follow-up in many centers. Retroperitoneal lymphadenectomy post-orchidectomy is the standard treatment for stage I nonseminomatous germ cell testicular tumors. Today, however, the foregoing approach is also being replaced by close postoperative follow-up.