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Updated: Oct 13, 2026

Germ Cell Transplantation and Testis Tissue Xenografting in Mice
Published on: February 6, 2012
[Surgical treatment of stage I germ cell tumor of the testis]
J Rubio Briones1, E Solsona Narbón
1Servicio de Urología, Instituto Valenciano de Oncología, Valencia, España.
Objective:
To analyze the current role of surgery in the treatment of stage I testicular germ cell tumors.
Methods:
We reviewed the literature on stage I testicular germ cell tumors. The technique of orchidectomy, the arguments in favor of retroperitoneal lymphadenectomy, the evolution of this technique and the prognostic factors that might be useful in determining the therapeutic approach to stage I testicular germ cell tumors are analyzed.
Results/Conclusions:
Treatment of testicular germ cell tumors should be performed in specialized centers that can offer all the therapeutic possibilities with a maximum guarantee so that the patient can decide on the treatment after receiving all the information on the advantages and disadvantages of each modality. Retroperitoneal lymphadenectomy with preservation of sympathetic innervation preserves ejaculation. Its cure rate is similar to that of other therapeutic options, it carries a minimum morbidity, follow-up is simplified, patient anxiety is reduced and there are long-term savings on costs.

