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Preparation and antidiabetic activity of new substituted 3,5-diarylpyrazolesulfonylurea derivatives. II:
R Soliman1, H M Faid-Allah, S K el-Sadany
1Department of Pharmaceutical Chemistry, College of Pharmacy, University of Alexandria, Egypt.
Journal of Pharmaceutical Sciences
|August 1, 1987
Abstract:
Four series of substituted p-(3,5-diaryl-2-pyrazoline-1) benzenesulfonylurea and thiourea derivatives, along with their corresponding substituted p-(3,5-diarylpyrazole-1) benzenesulfonylurea and thiourea derivatives, were prepared for evaluation as hypoglycemic agents. Preliminary biological testing revealed that the new compounds possess potent hypoglycemic activity.