Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Neonatal hypoxic-ischemic encephalopathy: detection with diffusion-weighted MR imaging.

K P Forbes1, J G Pipe, R Bird

  • 1Division of Neuroradiology, Barrow Neurological Institute, St Joseph's Hospital and Medical Center, AZ 85013, USA.

AJNR. American Journal of Neuroradiology
|September 26, 2000
PubMed
Summary

Diffusion-weighted imaging (DWI) shows limited sensitivity for detecting neonatal hypoxic-ischemic encephalopathy (HIE), especially when deep gray matter is involved. Conventional MRI may be more reliable for diagnosing HIE in neonates.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Haemodynamic response to pre-hospital emergency anaesthesia in trauma patients within an urban helicopter emergency medical service.

European journal of trauma and emergency surgery : official publication of the European Trauma Society·2024
Same author

Quality assessment grading of radiographs.

British dental journal·2023
Same author

Cosmic-ray antinuclei as messengers of new physics: status and outlook for the new decade.

Journal of cosmology and astroparticle physics·2021
Same author

Making the grade.

British dental journal·2021
Same author

Spiral T1 Spin-Echo for Routine Postcontrast Brain MRI Exams: A Multicenter Multireader Clinical Evaluation.

AJNR. American journal of neuroradiology·2020
Same author

Meta-analysis examining the epidemiology of clozapine-associated neutropenia.

Acta psychiatrica Scandinavica·2018

Area of Science:

  • Neonatal neurology
  • Neuroimaging
  • Pediatric radiology

Background:

  • Diffusion-weighted imaging (DWI) is sensitive for adult acute cerebral infarction.
  • Its efficacy in detecting neonatal hypoxic-ischemic encephalopathy (HIE) requires further evaluation.

Purpose of the Study:

  • To assess the ability of DWI to detect cerebral changes in acute neonatal HIE.
  • To compare DWI findings with conventional MRI in neonates with HIE.

Main Methods:

  • Fifteen MRI examinations were performed on 14 neonates diagnosed with HIE.
  • Conventional and echo-planar DWI sequences were utilized.
  • Comparison of lesion location, extent, and timing between conventional and DWI sequences and ADC maps.

Main Results:

Related Experiment Videos

  • Conventional MRI showed ischemic changes in all cases.
  • DWI detected signal hyperintensity and decreased ADC values in only 47% of subjects.
  • DWI sensitivity was higher for isolated cortical infarction than for deep gray matter involvement.

Conclusions:

  • DWI, with parameters used, may correlate less with clinical HIE than conventional MRI.
  • DWI sensitivity in neonatal HIE is influenced by the pattern of ischemic damage.
  • Lower sensitivity was observed when deep gray matter was affected compared to isolated cortical involvement.