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Published on: January 17, 2011
Reflux in children
1Gastroenterology Unit, Women's and Children's Hospital, 72 King William Road, North Adelaide, Adelaide, SA, 5006, Australia.
Insights
Gastro-oesophageal reflux (GOR) is common in children, often causing parental anxiety and unnecessary treatments. Advances in diagnostics and therapies are improving management for this pediatric condition.
Area of Science:
- Pediatric Gastroenterology
- Gastrointestinal Motility Disorders
Background:
- Gastro-oesophageal reflux (GOR) is a frequent pediatric issue, frequently benign but can cause significant parental distress.
- Physiological GOR can lead to excessive investigations and potentially harmful interventions.
Purpose of the Study:
- To review recent advances in understanding and managing pediatric gastro-oesophageal reflux and gastro-oesophageal reflux disease (GORD).
- To highlight improvements in diagnostic tools and therapeutic interventions for pediatric GOR/GORD.
Main Methods:
- Review of advancements in flexible endoscopy, 24-hour esophageal pH monitoring, and micromanometric methods for esophageal motility.
- Discussion of emerging non-invasive techniques like breath testing and electrical impedance.
- Overview of improved therapeutic strategies including acid suppression, surgical techniques, and laparoscopic fundoplication.
Main Results:
- Improved diagnostic capabilities allow for better definition of GOR and GORD in infants and children.
- Therapeutic interventions, particularly acid suppression and surgical approaches, have seen significant enhancements.
- Future advancements in non-invasive diagnostics are anticipated.
Conclusions:
- Recent progress has enhanced the ability to diagnose and manage pediatric GOR and GORD.
- Continued development in diagnostic and therapeutic modalities promises further improvements in patient care.
Abstract:
Gastro-oesophageal reflux (GOR) is an extremely common paediatric problem that often runs a harmless and self-limited course. Physiological GOR however can lead to marked parental anxiety, many unnecessary investigations and often unwarranted and potentially harmful therapeutic interventions. Our ability to better define GOR and gastro-oesophageal reflux disease (GORD) has improved in the past 15 years with a better understanding of the pathophysiology in infants and children due to the development and wider use of flexible endoscopy, 24-hour oesophageal pH monitoring and, more recently, the use of micromanometric methods for studying oesophageal motility. This will be further enhanced in the future with the development of non-invasive breath testing to study gastrointestinal motility and the use of electrical impedance to study fluid movement. Our therapeutic interventions have also improved particularly in the areas of acid suppression, improved surgical techniques and most recently laparoscopic fundoplication. This chapter reviews these advances in the paediatric area especially with regard to pathophysiology, diagnostic testing and therapeutic intervention.
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