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Related Experiment Videos

Nitric oxide reductases in bacteria.

J Hendriks1, A Oubrie, J Castresana

  • 1European Molecular Biology Laboratory, Meyerhofstrasse 1, Postfach 102209, D-69012, Heidelberg, Germany.

Biochimica Et Biophysica Acta
|September 27, 2000
PubMed
Summary
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This review details bacterial nitric oxide reductases (NORs), including cytochrome bc-type (cNOR) and quinol-dependent (qNOR) enzymes. It explores their roles and evolutionary links to cytochrome oxidases.

Area of Science:

  • Biochemistry
  • Microbiology
  • Enzymology

Background:

  • Nitric oxide reductases (NORs) are crucial enzymes in bacterial respiration.
  • NORs are part of the larger cytochrome oxidase enzyme family.
  • Two distinct types of bacterial NORs exist: cNOR and qNOR.

Purpose of the Study:

  • To review current knowledge on bacterial nitric oxide reductases.
  • To discuss the evolutionary relationships between NORs and cytochrome oxidases.

Main Methods:

  • Literature review of existing research on bacterial NORs.
  • Comparative analysis of cNOR and qNOR structures and functions.
  • Evolutionary analysis of NORs and cytochrome oxidases.

Main Results:

Related Experiment Videos

  • Characterization of two bacterial NOR types: cNOR and qNOR.
  • qNOR is found in pathogens and does not require a cytochrome c donor.
  • NORs share evolutionary links with cytochrome oxidases.

Conclusions:

  • Bacterial NORs represent a diverse enzyme group with significant roles in microbial metabolism.
  • Understanding NORs and their evolutionary history provides insights into bacterial adaptation and enzyme evolution.