Related Experiment Video
Updated: Oct 13, 2026
A Murine Model of Group B Streptococcus Vaginal Colonization
Published on: November 16, 2016
Preventive procedures against GBS infection by means of antibody measurement
1Department of Obstetrics and Gynecology, School of Medicine, Gifu University, Japan. mikamo@cc.gifu-u.ac.jp
Objective:
Screening group B Streptococcus (GBS) in the vagina of pregnant women and measuring serum level of its type-specific antibody would be useful for cost-benefit of the prevention against GBS infection.
Study Design:
The subjects included a total of 1,150 pregnant women who consented to the study. Serotypes of GBS detected were classified with antiserum. Serum type-specific antibody titers were measured by a bacterial agglutination method.
Results:
Of a total of 1,150 pregnant women, 250 cases (21.7%) had GBS in the vagina. The turn of GBS serotype occurrence was types VI (NT6) (27. 2%), VIII (JM9) (25.2%), III (11.2%), Ia (8.8%), and Ib (8.0%). None or low type-specific antibody titer was 41.0% of Ia, 20.0% of Ib, 22. 0% of II, 15.0% of III, 65.0% of VI, and 69.0% of VIII incarriers. Noneonatal GBS infection occurred under the empirically treatment.
Conclusion:
The measurement of serum type-specific antibody against GBS would be informative for the cost-benefit treatment of the vaginal GBS in pregnant women.
