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Related Experiment Videos

Spatial resolution of epicardial pace mapping using body surface potentials.

S Samarin1, R Hren, R Trobec

  • 1Department of Cardiovascular Surgery, Medical Center Ljubljana, Slovenia. samarinsilvia@hotmail.com

Pflugers Archiv : European Journal of Physiology
|September 27, 2000
PubMed
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Body surface potential mapping can non-invasively identify cardiac pacing sites. This study shows epicardial pacing sites are resolvable within 10 mm using body surface ECGs, aiding ventricular tachycardia ablation.

Area of Science:

  • Cardiology
  • Biomedical Engineering
  • Medical Imaging

Background:

  • Body surface potential mapping (BSPM) is a non-invasive technique for localizing cardiac electrical events.
  • Previous studies established high spatial resolution (<10 mm) for endocardial pacing sites using BSPM.
  • The efficacy of BSPM for epicardial pacing sites remained to be determined.

Purpose of the Study:

  • To assess if BSPM can achieve similar spatial resolution for epicardial pacing sites as previously shown for endocardial sites.
  • To evaluate the feasibility of non-invasively resolving epicardial breakthrough sites within 10 mm.

Main Methods:

  • Four cardiac surgery patients underwent intraoperative placement of epicardial electrodes on the right ventricle (10 mm apart).
  • Post-surgery, 35-lead ECGs were recorded during pacing from each electrode.

Related Experiment Videos

  • QRS integral distributions were mapped and statistically compared between pacing sites using Student's t-test.
  • Main Results:

    • Statistically significant differences (p < 0.01) in QRS integral map distributions were observed between pacing from adjacent epicardial electrodes in all patients.
    • This indicates that epicardial breakthrough sites could be distinguished.

    Conclusions:

    • Non-invasive body surface ECG acquisition can resolve epicardial breakthrough sites within 10 mm.
    • This technique holds potential for guiding therapeutic ablations in ventricular tachycardia patients.