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Mechanisms of chronic rejection
A M Waaga1, M Gasser, I Laskowski
1Surgical Research Laboratory, Harvard Medical School, Brigham and Women's Hospital, Boston, MA 02115, USA.
Current Opinion in Immunology
|September 28, 2000
Abstract:
Chronic rejection remains the major obstacle to long-term allograft survival. Detailed understanding of putative etiologic risk factors, both antigen-dependent and -independent, is important for designing effective therapeutic strategies to ameliorate this process. Cell senescence may be an important factor in chronic rejection.