Related Experiment Videos
Bartonella henselae, B. quintana, and B. bacilliformis: historical pathogens of emerging significance
K L Karem1, C D Paddock, R L Regnery
1Viral and Rickettsial Zoonoses Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, US Department of Health and Human Services, Atlanta, Georgia 30333, USA.
Abstract:
Bartonella species were virtually unrecognized as modern pathogens of humans until the last decade. However, identification of Bartonella species as the agents of cat-scratch disease, bacillary angiomatosis, urban trench fever, and possible novel presentations of Carrion's disease has left little doubt of the emerging medical importance of this genus of organisms. The three primary human pathogenic bartonellae, Bartonella bacilliformis (Carrion's disease), B. henselae (cat-scratch disease), and B. quintana (trench fever), present noteworthy comparisons in the epidemiology, natural history, pathology, and host-microbe interaction that this review will briefly explore.
Insights
Bartonella bacteria are emerging human pathogens causing diseases like cat-scratch disease and trench fever. This review explores key comparisons of three primary Bartonella species affecting humans.
Area of Science:
- Medical microbiology
- Infectious diseases
- Bacteriology
Background:
- Bartonella species have recently gained recognition as significant human pathogens.
- Previously, their role in human illness was largely underestimated.
Observation:
- Bartonella species are now identified as causative agents of cat-scratch disease, bacillary angiomatosis, urban trench fever, and potentially new forms of Carrion's disease.
- This genus represents a growing medical concern.
Findings:
- The review focuses on three main human pathogenic Bartonella species: Bartonella bacilliformis (Carrion's disease), Bartonella henselae (cat-scratch disease), and Bartonella quintana (trench fever).
- Comparative analysis covers epidemiology, natural history, pathology, and host-microbe interactions.
Implications:
- Understanding these comparisons is crucial for diagnosing and managing Bartonella-related infections.
- Highlights the emerging importance of Bartonella in public health and clinical practice.