Related Experiment Videos
A new flavonoid from Limonium axillare
F E Kandil1, K M Ahmed, H A Hussieny
1Chemistry of Tanning Materials and Proteins Dept., National Research Centre, Dokki, Cairo, Egypt.
Archiv Der Pharmazie
|September 29, 2000
Summary
A novel compound, myricetin 3-O-beta-D-sorboside, was isolated from L. axillare leaves. This new flavonol glycoside demonstrated moderate inhibition against Ehrlich ascites carcinoma cells in preliminary tests.
Area of Science:
- Phytochemistry
- Natural Products Chemistry
- Pharmacology
Background:
- L. axillare is a plant species with potential medicinal properties.
- Flavonol glycosides are a class of natural compounds known for diverse biological activities.
Purpose of the Study:
- To isolate and identify new compounds from L. axillare leaves.
- To evaluate the cytotoxic activity of isolated compounds against cancer cells.
Main Methods:
- Phytochemical investigation of L. axillare leaf extract.
- Isolation and structural elucidation of the new compound using spectroscopic methods.
- In vitro cytotoxic assay against Ehrlich ascites carcinoma cells.
Main Results:
- A new flavonol glycoside, myricetin 3-O-beta-D-sorboside (1), was successfully isolated and characterized.
- Compound (1) exhibited moderate inhibitory effects on the proliferation of Ehrlich ascites carcinoma cells.
Conclusions:
- Myricetin 3-O-beta-D-sorboside is a novel compound isolated from L. axillare.
- The findings suggest potential anticancer properties of this new flavonol glycoside, warranting further investigation.