Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Intracellular Signaling Cascades01:24

Intracellular Signaling Cascades

Once a ligand binds to a receptor, the signal is transmitted through the membrane and into the cytoplasm. The continuation of a signal in this manner is called signal transduction. Signal transduction only occurs with cell-surface receptors, which cannot interact with most components of the cell, such as DNA. Only internal receptors can interact directly with DNA in the nucleus to initiate protein synthesis. When a ligand binds to its receptor, conformational changes occur that affect the...
Intracellular Signaling Cascades01:24

Intracellular Signaling Cascades

Once a ligand binds to a receptor, the signal is transmitted through the membrane and into the cytoplasm. The continuation of a signal in this manner is called signal transduction. Signal transduction only occurs with cell-surface receptors, which cannot interact with most components of the cell, such as DNA. Only internal receptors can interact directly with DNA in the nucleus to initiate protein synthesis. When a ligand binds to its receptor, conformational changes occur that affect the...
Amplifying Signals via Second Messengers01:15

Amplifying Signals via Second Messengers

Many receptor binding ligands are hydrophilic; they do not cross the cell membrane but bind to cell-surface receptors. Thus, their message must be relayed by second messengers present in the cell cytoplasm. There are several second messenger pathways, each with its own way of relaying information. For example, the G protein-coupled receptors can activate both phosphoinositol and cyclic AMP (cAMP) second messenger pathways. The phosphoinositol pathway is active when the receptor induces...
Signal Transduction: Overview01:26

Signal Transduction: Overview

Cells respond to many types of information, often through receptor proteins positioned on the membrane. They respond to chemical signals, such as hormones, neurotransmitters, and other signaling molecules, initiating a series of molecular reactions to produce an appropriate response. This is called signal transduction. Cells also coordinate different responses elicited by the same signaling molecule via mediators, allowing molecular cross-talk.
Typically, signal transduction involves three...
Signal and System01:26

Signal and System

A signal x(t) is a set of data or a time function representing a variable of interest. Signals typically convey information about a phenomenon, such as atmospheric temperature, humidity, human voice, television images, a dog's bark, or birdsongs. More generally, a signal can be a function of more than one independent variable. For instance, images depend on horizontal and vertical positions and can be regarded as two-dimensional signals. However, this text will focus on one-dimensional signals...
Classification of Signals01:30

Classification of Signals

In signal processing, signals are classified based on various characteristics: continuous-time versus discrete-time, periodic versus aperiodic, analog versus digital, and causal versus noncausal. Each category highlights distinct properties crucial for understanding and manipulating signals.
A continuous-time signal holds a value at every instant in time, representing information seamlessly. In contrast, a discrete-time signal holds values only at specific moments, often denoted as x(n), where...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Trio united by division as cell cycle clinches centenary Nobel.

Nature·2001
Same author

Antigen persistence in HIV resistance.

Nature medicine·2001
Same author

Research News.

Nature medicine·2001
Same author

Analysis of Myc/Max/Mad network members in adipogenesis: inhibition of the proliferative burst and differentiation by ectopically expressed Mad1.

Journal of cellular physiology·2000
Same author

The Mad protein family links transcriptional repression to cell differentiation.

Cold Spring Harbor symposia on quantitative biology·1999
Same author

Activation of the cellular transcription factor AP-1 in herpes simplex virus infected cells is dependent on the viral immediate-early protein ICPO.

Nucleic acids research·1991

Related Experiment Video

Updated: Jun 26, 2026

Mimicking the Function of Signaling Proteins: Toward Artificial Signal Transduction Therapy
12:24

Mimicking the Function of Signaling Proteins: Toward Artificial Signal Transduction Therapy

Published on: September 29, 2016

Signal transduction. An arresting tale

B Pulverer

    Nature
    |September 30, 2000
    PubMed
    Summary

    No abstract available in PubMed .

    More Related Videos

    Transmission of Multiple Signals through an Optical Fiber Using Wavefront Shaping
    09:43

    Transmission of Multiple Signals through an Optical Fiber Using Wavefront Shaping

    Published on: March 20, 2017

    Using Extraordinary Optical Transmission to Quantify Cardiac Biomarkers in Human Serum
    09:23

    Using Extraordinary Optical Transmission to Quantify Cardiac Biomarkers in Human Serum

    Published on: December 13, 2017

    Related Experiment Videos

    Last Updated: Jun 26, 2026

    Mimicking the Function of Signaling Proteins: Toward Artificial Signal Transduction Therapy
    12:24

    Mimicking the Function of Signaling Proteins: Toward Artificial Signal Transduction Therapy

    Published on: September 29, 2016

    Transmission of Multiple Signals through an Optical Fiber Using Wavefront Shaping
    09:43

    Transmission of Multiple Signals through an Optical Fiber Using Wavefront Shaping

    Published on: March 20, 2017

    Using Extraordinary Optical Transmission to Quantify Cardiac Biomarkers in Human Serum
    09:23

    Using Extraordinary Optical Transmission to Quantify Cardiac Biomarkers in Human Serum

    Published on: December 13, 2017