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Continuous infusion of recombinant activated factor VII during caesarean section delivery in a patient with

V Jiménez-Yuste1, A Villar, M Morado

  • 1Hemophilia Centre, Department of Hematology, La Paz University Hospital, Madrid, Spain.

Haemophilia : the Official Journal of the World Federation of Hemophilia
|September 30, 2000
PubMed

Recombinant activated factor VII (rFVIIa) can be used as an alternative therapy in patients with FVII deficiency. However, as the drug has a very short half-life, continuous infusion could be a meaningful administration modality. We report the case of a 30-year-old woman with moderate FVII deficiency and human immunodeficiency virus infection who underwent a caesarean section delivery. She was treated with a continuous infusion of rFVIIa and did not suffer any bleeding complication. The continuous infusion of rFVIIa was a safe and effective therapeutic approach for our patient, maintaining her levels of FVII:C and avoiding bleeding during caesarean section and afterwards.

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