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Related Experiment Videos

Ascaris and ascariasis.

D W Crompton1

  • 1WHO Collaborating Centre for Soil-transmitted Helminthiases, Institute of Biomedical and Life Sciences, University of Glasgow, UK.

Advances in Parasitology
|October 3, 2000
PubMed
Summary
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Ascariasis, caused by Ascaris lumbricoides, is a significant public health issue. Regular deworming of schoolchildren with anthelminthic drugs is a cost-effective control strategy, though eradication is unlikely due to poor sanitation.

Area of Science:

  • Parasitology
  • Public Health
  • Epidemiology

Background:

  • Recent research has advanced understanding of Ascaris lumbricoides epidemiology and its public health impact.
  • Experimental studies on Ascaris suum in pigs inform human ascariasis observations.
  • The relationship between A. lumbricoides and A. suum in co-infected communities is being investigated.

Purpose of the Study:

  • To review new information on ascariasis to promote its recognition as a major cause of ill-health.
  • To guide the development and implementation of sustainable control programs for Ascaris lumbricoides infections.
  • To assess the feasibility of eradication versus control strategies for ascariasis.

Main Methods:

  • Literature review synthesizing recent findings on ascariasis epidemiology, biology, and control.

Related Experiment Videos

  • Analysis of evidence supporting the efficacy of anthelminthic drug administration in children.
  • Examination of host immune responses and vaccine development prospects.

    • Main Results:

    • Ascariasis is a significant contributor to global ill-health, necessitating effective control measures.
    • Regular deworming of primary school children with broad-spectrum anthelminthic drugs is a cost-effective control method.
    • Drug resistance detection and management are crucial for sustained efficacy of control programs.

    Conclusions:

    • Eradication of ascariasis is not currently feasible due to widespread sanitation issues.
    • Sustainable control programs focusing on morbidity reduction through regular deworming are recommended.
    • While understanding of immune responses has grown, effective vaccines against ascariasis are not yet available.