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Updated: Jul 25, 2026

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Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
Published on: May 25, 2020
Optic nerve evaluation among optometrists.
J M Spalding1, A B Litwak, C L Shufelt
1Orlando VA Healthcare Center, Florida 32803, USA.
Summary
Optometrists
Area of Science:
- Ophthalmology and Optometry
- Glaucoma Diagnosis
- Optic Nerve Imaging
Background:
- Accurate assessment of optic nerve head (ONH) features is crucial for glaucoma diagnosis.
- Cup-to-disk (C/D) ratio estimation and identification of glaucomatous damage are key diagnostic steps.
- Variability in ONH assessment among clinicians can impact patient care.
Purpose of the Study:
- To evaluate agreement among optometrists in assessing optic nerve C/D ratios and glaucomatous damage.
- To analyze how residency training, practice setting, and glaucoma patient experience influence these assessments.
- To determine interobserver and intraobserver agreement levels.
Main Methods:
- Fifty-six optometrists evaluated 33 stereoscopic optic nerve photographs.
- Participants estimated vertical C/D ratios and determined glaucomatous status.
- Interobserver and intraobserver agreement were calculated using kappa statistics.
Main Results:
- Optometrists' C/D ratio estimations and glaucoma damage interpretations varied significantly based on training, practice setting, and experience.
- Higher interobserver agreement for C/D ratios and glaucomatous damage was observed among residency-trained optometrists and those in clinical settings.
- Agreement was notably higher for optometrists with residency training and those practicing in clinical settings (e.g., optometry schools, medical centers).
Conclusions:
- Intraobserver agreement exceeded interobserver agreement for both C/D ratio estimation and glaucomatous damage assessment.
- Residency training, practice environment, and the volume of glaucoma patient encounters significantly influence optometrists' optic nerve evaluations.
- Standardization of ONH assessment criteria may be beneficial to improve diagnostic consistency.
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