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Comorbidity assessment in hemodialysis and peritoneal dialysis using the index of coexistent disease

N V Athienites1, D C Miskulin, G Fernandez

  • 1Department of Medicine, Primary Care Outcomes Research Institute, New England Medical Center, Boston, Massachusetts 02111, USA.

Seminars in Dialysis
|October 3, 2000
PubMed

Insights

This study introduces the Integrated Comorbidity Estimation and Description (ICED) tool for assessing patient health complexity. The ICED effectively quantifies comorbid conditions in dialysis patients, linking higher ICED scores to poorer outcomes in peritoneal dialysis patients.

Area of Science:

  • Nephrology
  • Clinical Epidemiology
  • Health Services Research

Background:

  • Comorbidities significantly impact patient outcomes in chronic kidney disease.
  • Accurate quantification of comorbidity burden is essential for clinical management and research.
  • Existing instruments may not fully capture the complexity of comorbid conditions in dialysis populations.

Purpose of the Study:

  • To describe the Integrated Comorbidity Estimation and Description (ICED) instrument.
  • To summarize prior study outcomes utilizing the ICED.
  • To demonstrate the ICED's application in quantifying comorbidity burden among hemodialysis and peritoneal dialysis patients and its association with patient outcomes.

Main Methods:

  • Description and adaptation of the Integrated Comorbidity Estimation and Description (ICED) instrument.
  • Application of the ICED to quantify comorbid conditions in a cohort of hemodialysis and peritoneal dialysis patients.
  • Statistical analysis to explore the relationship between ICED scores and patient outcomes, particularly in peritoneal dialysis.

Main Results:

  • The study details the development and validation of the ICED instrument.
  • The ICED successfully quantified comorbidity burden in the studied dialysis patient sample.
  • Higher ICED scores were associated with adverse outcomes in peritoneal dialysis patients, highlighting its predictive utility.

Conclusions:

  • The Integrated Comorbidity Estimation and Description (ICED) is a valuable tool for assessing comorbidity burden in dialysis patients.
  • ICED facilitates a deeper understanding of how comorbid conditions influence patient outcomes.
  • Further research utilizing the ICED can inform clinical practice and improve care for patients with kidney disease.

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