Related Experiment Video
Updated: Oct 11, 2026

A New Method for Inducing a Depression-Like Behavior in Rats
Published on: February 22, 2018
Internalizing problems of childhood and adolescence: prospects, pitfalls, and progress in understanding the
C Zahn-Waxler1, B Klimes-Dougan, M J Slattery
1Section on Developmental Psychopathology, Child Psychiatry Branch, National Institute of Mental Health Bethesada, MD 20892, USA.
Abstract:
The focus of this article is on internalizing problems that are experienced by children and adolescents. We provide an historical perspective, selectively examine the current state of knowledge, consider advances and gaps in what is known, and identify new research directions. Diagnosis, epidemiology, theory, and research first are considered separately for anxiety and depressive disorders. These internalizing problems, however, whether clinical or subclinical, share many common features and show high comorbidity rates. We emphasize the importance of systematic analysis of comorbid anxiety and depression, including their comorbidity with externalizing problems. This could lead to more valid classification of subtypes of internalizing problems and further an understanding of the diverse conditions that constitute internalized distress. We highlight the need to study anxiety and depression within a developmental psychopathology framework, as well as to include both categorical and dimensional assessments of these problems in the same research designs. This will be essential for understanding the complex interplay of biological and environmental processes that contribute to the emergence, progression, and amelioration of internalizing problems over time.
Related Concept Videos
Depressive Disorders: Etiology
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Erikson's Theory on Socioemotional Development during Childhood
The first four of Erikson's eight psychosocial stages...
Social Anxiety Disorder
Self-Discrepancy and Its Effects
Cognitive Development During Adolescence
Socioemotional Development during Infancy
Primary Temperament Types
Stella Chess...