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Implementation of In Vitro Drug Resistance Assays: Maximizing the Potential for Uncovering Clinically Relevant Resistance Mechanisms
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Impact of mechanism-based enzyme inactivation on inhibitor potency: implications for rational drug discovery

T S Maurer1, M A Tabrizi-Fard, H L Fung

  • 1Department of Pharmaceutics, School of Pharmacy, University at Buffalo, State University of New York, Buffalo, New York 14260-1200, USA. tristan_s_maurer@groton.pfizer.com

Journal of Pharmaceutical Sciences
|October 4, 2000
PubMed

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