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Antepartum findings in fetal protein C deficiency

P Kirkinen1, M Salonvaara, K Nikolajev

  • 1Department of Obstetrics and Gynaecology, University of Kuopio, Finland. Pertti.Kirkinrn@KUH.fi

Prenatal Diagnosis
|October 4, 2000
PubMed

Abstract:

A pregnancy with fetal homozygous protein C deficiency was complicated in the third trimester by fetal ventriculomegaly, intraorbital thrombosis and placental infarcts, which could be imaged by combined use of ultrasonography and MRI.

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The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...

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