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[Immunomodulation of pain]
1Katedra i Zakład Anatomii Prawidłowej Akademii Medycznej im. K. Marcinkowskiego w Poznaniu.
Postepy Higieny I Medycyny Doswiadczalnej
|October 4, 2000
Abstract:
Review of the interacting elements of nociceptive, neuroimmune and neuroendocrine systems with a stress on sympathetic innervation of the lymphoid organs. Special attention is given to dysfunctions within the nociceptive, neuroendocrine and immune systems due to: damage to the: 1) afferent fibers; 2) sympatho-adrenal system; 3) structure of the hypothalamo-pituitary-adrenal axis. The role of peripheral immunocytes in the generation of pain, including local cytokines, opioids and CRF is also discussed.