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Vancomycin-induced neutropenia resolves after substitution with teicoplanin
S E Sanche1, W N Dust, Y M Shevchuk
1Division of Infectious Diseases, Royal University Hospital, Saskatoon, SK, Canada. sanche@duke.usask.ca
Abstract:
Neutropenia is an uncommon adverse effect associated with prolonged vancomycin therapy. Neutrophil counts normally recover after discontinuation of vancomycin in this situation, but treatment options are needed for those patients who require ongoing antibiotic therapy. We describe a case of vancomycin-induced neutropenia in which the neutropenia resolved after vancomycin was replaced by the structurally related compound teicoplanin.