Immunocytochemical localization of cathepsin D in rabbit skin

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Updated: Nov 5, 2026

Immunohistochemistry on Paraffin Sections of Mouse Epidermis Using Fluorescent Antibodies
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Immunohistochemistry on Paraffin Sections of Mouse Epidermis Using Fluorescent Antibodies

Published on: January 8, 2008

G S Lazarus, A R Poole

    Archives of Dermatology
    |September 1, 1975
    PubMed

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    Immunocytochemistry and Immunohistochemistry

    Immunocytochemistry (ICC) and immunohistochemistry (IHC) are techniques that use antibodies to check for specific proteins or antigens in a sample. The technique was first published by Albert Coons in 1941 to detect the presence of pneumococcal antigen in tissue sections from mice infected with Pneumococcus. Immunocytochemistry helps localization of proteins or antigens in individual cells like blood cells, stem cells, etc., while immunohistochemistry does the same for tissue samples.
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